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Effect of Lethally Irradiated Cells on the Development of New-Born Rats

Abstract

DURING work dealing with the heterotransplantation of hyperdiploid (E/Dipl) and hypotetraploid (E/Sto) variants of Ehrlich's ascites tumour into rats exposed to total-body X-ray irradiation1, I established a difference in the effect of the same inoculum of these two variants of Ehrlich's ascites tumour on the survival of rats. The effect of the tumour of these two variants previously irradiated with a lethal dose of 12,000 r. and implanted into rats exposed to total-body irradiation has been found to be of a much smaller degree, there being a difference in the effect of the two tumour variants.

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References

  1. Klímek, M., Neoplasma, 8, 3 (1961).

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  2. Drášil, V., Neoplasma, 8, 2 (1961).

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  3. Revesz, L., J. Nat. Cancer Inst., 25, 5, 1041 (1960).

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KLÍMEK, M. Effect of Lethally Irradiated Cells on the Development of New-Born Rats. Nature 193, 996–997 (1962). https://doi.org/10.1038/193996a0

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