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Membrane Potential Changes during Sodium Transport in Frog Sartorius Muscle

Nature volume 193, pages 986–987 (1962)Cite this article

Abstract

THE concept of a sodium–potassium linked electrically neutral pump was first put forward by Hodgkin1 for muscle and nerve. He suggested that a potassium ion might be transported into the cell for each sodium ion actively extruded, leading to an electrical neutrality with respect to the operation of the sodium-pump. This idea has been tested in the following experiments.

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References

  1. Hodgkin, A. L., Proc. Roy. Soc., B, 148, 1 (1957).

    Article  ADS  Google Scholar 

  2. Graham, J., and Gerard, R. W., J. Cell. Comp. Physiol., 29, 99 (1946).

    Article  Google Scholar 

  3. Desmedt, J. E., J. Physiol., 121, 191 (1953).

    Article  CAS  Google Scholar 

  4. Carey, M. J., Conway, E. J., and Kernan, R. P., J. Physiol., 148, 51 (1959).

    Article  CAS  Google Scholar 

  5. Conway, E. J., Kernan, R. P., and Zadunaisky, J. A., J. Physiol., 155, 263 (1961).

    Article  CAS  Google Scholar 

  6. Hodgkin, A. L., and Horowicz, P., J. Physiol., 148, 127 (1959).

    Article  CAS  Google Scholar 

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  1. Department of Biochemistry, University College, Dublin

    RODERICK P. KERNAN

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  1. RODERICK P. KERNAN
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KERNAN, R. Membrane Potential Changes during Sodium Transport in Frog Sartorius Muscle. Nature 193, 986–987 (1962). https://doi.org/10.1038/193986a0

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