Abstract
INVESTIGATIONS were carried out with a streptomycin-sensitive strain of V. comma A.T.C.C. 9168, believed to be lysogenic. It was found that under specific environmental conditions such as reduced redox potential, brought about by thioglycollate, the bacteria lyse. In lysing they liberate a substance lethal to part of the homologous population. Streptomycin-resistant mutants, derived from the strain, were sensitive to the inhibitor but only when tested aerobically. Thus, under the latter conditions streptomycin-resistant mutants served as an indicator strain for the presence of inhibitor.
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FARKAS-HIMSLEY, H., SEYFRIED, P. Lethal Biosynthesis of a New Antibacterial Principle: Vibriocin. Nature 193, 1193–1194 (1962). https://doi.org/10.1038/1931193a0
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DOI: https://doi.org/10.1038/1931193a0
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