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In vitro Culture of a Leukæmic Agent from Spontaneous Mouse Leukæmia

Abstract

SEVERAL attempts have been made to propagate leukæmogenic agents in tissue culture. Gross's passage A1, Friend's2,3 and Moloney's4,5 viruses have been grown, with varying success. Graffi's agent failed to yield positive results, so far as we know6. Werder and associates reported “successful attempts … to transfer … filterable agents … in tissue culture”, but no details were given7.

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References

  1. Gross, L., Dreyfus, Y., and Moore, L. A., Proc. Amer. Assoc. Cancer Res., 3, 231 (1961).

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  2. Moore, A. E., and Friend, C., Proc. Amer. Assoc. Cancer Res., 2, 328 (1958).

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  3. Vigier, P., Latarjet, R., and Goldé, A., quoted by Gross, L., Oncogmic Viruses, 267 (Pergamon Press, London, 1961).

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  4. Manaker, R. A., Strother, P. C., Miller, A. A., and Piczak, C. V., J. Nat. Cancer Inst., 25, 1411 (1960).

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  7. Werder, A. A., Martin, D., and Hardin, C., Fed. Proc., 18, 513 (1959).

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  9. Clode, M., Lemonde, P., and Pavilanis, V., Annales Assoc. Canad. Fr. Avanc. Sci., 28 (in the press).

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LEMONDE, P., CLODE, M. In vitro Culture of a Leukæmic Agent from Spontaneous Mouse Leukæmia. Nature 193, 1191–1192 (1962). https://doi.org/10.1038/1931191a0

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