Abstract
THIS communication reports the results of analytical ultracentrifuge analyses on sera of 50 acutely mentally disturbed patients. Sera were taken within 24 hr. of admission to hospital and prior to institution of definitive therapy. Phenothiazine, monoamine oxidase inhibitor or electroshock therapy had not been given to any patient during the three months prior to serum collection. The diagnoses were varied; but all patients had an acute mental disturbance of sufficient severity to warrant hospital admission. Consecutively admitted patients were used excluding only those with known organic brain disease, alcoholism and those known to have had drug or electro-shock treatment during the previous three months. Sera of 48 blood bank donors were used as controls. Sera were stored at −15° C. until analysis, which was usually within 8 weeks of collection. (Analytical ultracentrifuge examinations were made by the Institute of Medical Physics, Belmont, California.)
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FESSEL, W. Macroglobulin Elevations in Functional Mental Illness. Nature 193, 1005 (1962). https://doi.org/10.1038/1931005a0
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DOI: https://doi.org/10.1038/1931005a0
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