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Isolation of Histones(?) from Staphylococcus aureus

Abstract

ANY theories that try to give an explanation of the function of histones have had in the past to take account of the reported absence of histones from bacteria1,2. If histones are solely concerned with cell differentiation or ‘gene suppression’ in multicellular organisms, then one might expect them to be absent from bacteria and protozoa3,4. But if, on the other hand, they have an even more fundamental function, related to the function of deoxyribonucleic acid (DNA) in all cells, then they should also be present in unicellular organisms.

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CRUFT, H., LEAVER, J. Isolation of Histones(?) from Staphylococcus aureus. Nature 192, 556–557 (1961). https://doi.org/10.1038/192556b0

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