Abstract
AS already stated1, some synthetic polypeptide derivatives exhibit considerable antitubercular activity. These antibacterial polypeptide derivatives were prepared from poly-α-aminodicarboxylic-acidesters (for example, polymethyl-α-poly-L-glutamate, polymethyl-α-poly-DL-aminoadipate) and from poly-aminodicarboxylic-acid-anhydrides (for example, anhydro-poly-aspartic-acid) with diamines (ethylene-diamine, β-dialkylethylenediamines)2.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Kovács, K., Kótai, A., and Szabó, I., Nature, 185, 266 (1960).
Kovács, K., and Kótai, A., Acta Chim. Hung., 21, 453 (1959). Kótai, A., Kovács, K., and Császár, J., ibid., 21, 461 (1959).
Anderson, C. G., Intro. to Bact. Chem., 106 (Williams and Wilkins Co., Baltimore, 1948).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
KOVÁCS, K., KÓTAI, A., SZABÓ, I. et al. Antibacterial Synthetic Polypeptide Derivatives. Nature 192, 190–191 (1961). https://doi.org/10.1038/192190a0
Issue Date:
DOI: https://doi.org/10.1038/192190a0
This article is cited by
-
Polycationic modified polypeptides enhancing poly I:C induced viral resistance
Experientia (1975)
-
The experimental production of hemorrhagic lesions in the rat adrenal, liver and lung by basic polyglutamic acid derivatives
Research in Experimental Medicine (1972)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.