Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Mediation of Divalent Metal Ions in the Binding of Tetracycline to Macromolecules

Nature volume 191, pages 1156–1158 (1961)Cite this article

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Rokos, J., Burger, M., and Prochezka, P., Nature, 181, 1201 (1958); Antibiot. Chemother., 9, 600 (1959).

    Article  ADS  CAS  Google Scholar 

  2. Lacko, L., Korinek, J., and Burger, M., Clin. Chim. Acta, 4, 800 (1959).

    Article  CAS  Google Scholar 

  3. Rall, D. P., Loo, T. L., Lane, M., and Kelly, M. G., J. Nat. Cancer Inst., 19, 79 (1957).

    CAS  Google Scholar 

  4. Lane, M., Titus, E., and Loo, T. L. (unpublished experiments indicating that the tetracycline complex in tumours is dissociated by EDTA).

  5. Albert, A., Nature, 172, 201 (1953); 177, 433 (1956).

    Article  ADS  CAS  Google Scholar 

  6. Milch, R. A., Rall, D. P., and Tobie, J. E., J. Bone and Joint Surg., 40, A, 897 (1958).

    Article  Google Scholar 

  7. Bevelander, G., Nakahara, H. and Rolle, G. K., Developmental Biol., 2, 298 (1960).

    Article  CAS  Google Scholar 

  8. Kohn, K., Anal. Chem., 33, 862 (1961).

    Article  CAS  Google Scholar 

  9. Shack, J., J. Biol. Chem., 233, 677 (1958).

    PubMed  CAS  Google Scholar 

  10. Hoch, F. L. and Vallee, B. L., Anal. Chem., 25, 317 (1953).

    Article  CAS  Google Scholar 

  11. Klotz, I. M., and Loh Ming, W. C., J. Amer. Chem. Soc., 76, 805 (1954).

    Article  CAS  Google Scholar 

  12. Vallee, B. L., Coombs, T. L., and Williams, R. J. P., J. Amer. Chem. Soc., 80, 397 (1958).

    Article  CAS  Google Scholar 

  13. Zubay, G., and Doty, P., Biochim. Biophys. Acta, 29, 47 (1958).

    Article  CAS  Google Scholar 

  14. Gurd, F. R. N., and Goodman, D. S., J. Amer. Chem. Soc., 74, 670 (1959).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Clinical Pharmacology and Experimental Therapeutics Service, General Medicine Branch, National Cancer Institute, Bethesda, Maryland

    KURT W. KOHN

Authors
  1. KURT W. KOHN
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

KOHN, K. Mediation of Divalent Metal Ions in the Binding of Tetracycline to Macromolecules. Nature 191, 1156–1158 (1961). https://doi.org/10.1038/1911156a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/1911156a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing