Abstract
COAGULASE-POSITIVE strains of Staphylococcus pyogenes, taken at random from material phage-typed at Hammersmith Hospital and at the Central Public Health Laboratory, Colindale, were tested for their nutritional character. All but 50 of the 926 strains grew well on a defined medium (based on that of Fildes et al.1) containing valine, leucine, glycine, proline, aspartic acid, methionine, phenylalanine, arginine, histidine, cysteine, thiamine and nicotinic acid in a glucose-citrate-salts-agar base. Of the 50 exacting strains, all but 4 grew on the medium further supplemented as follows : tryptophan, 12 strains ; threonine, 6 strains ; alanine, 4 strains; tyrosine, 3 strains; lysine, 2 strains; tryptophan and tyrosine, 9 strains; tryptophan and isoleucine, 2 strains; tryptophan and biotin, 2 strains; threonine and glutamic acid, 1 strain; biotin, 2 strains; riboflavine, 1 strain; hypoxanthine, 2 strains.
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References
Fildes, P., Richardson, G. M., Knight, B. C. J. G., and Gladstone, G. P., Brit. J. Exp. Path., 17, 481 (1936).
Roberts, R. B., et al., Carnegie Inst. Wash. Publ., 607 (1955).
Morse, M. L., Proc. U.S. Nat. Acad. Sci., 45, 722 (1959).
Glanville, E. V., and Demerec, M., Genetics, 45, 1359 (1960).
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EDGAR, J., STOCKER, B. Metabolic and Genetic Investigations of Nutritionally Exacting Strains of Staphylococcus pyogenes. Nature 191, 1121–1122 (1961). https://doi.org/10.1038/1911121a0
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DOI: https://doi.org/10.1038/1911121a0
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