Abstract
KNOWLEDGE of prejunctional events in neuromuscular transmission is at present indirect in origin and largely speculative in content. This is because there has been no method of directly recording from, or stimulating, the very small motor nerve endings. Using a glass micro-electrode in the isolated rat diaphragm phrenic nerve preparation we have succeeded in stimulating single nerve fibres very close to, or at, the neuromuscular junction. The recording chamber and bathing solution have been previously described1.
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References
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HUBBARD, J., SCHMIDT, R. Stimulation of Motor Nerve Terminals. Nature 191, 1103–1104 (1961). https://doi.org/10.1038/1911103a0
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DOI: https://doi.org/10.1038/1911103a0
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