Abstract
WHEN plastic material is used as a biological implant, to improve contour or function, one of four things commonly occurs: it may cause an acute inflammatory episode and be rejected; rejection may be delayed for several months or years; it may be removed piecemeal by the body's own phagocytes; it may become encysted by fibrous tissue and remain in situ. In the last situation the implant has become virtually extracorporeal.
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CALNAN, J. Biological Incorporation of Implant Material in the Rat. Nature 191, 1017–1018 (1961). https://doi.org/10.1038/1911017b0
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DOI: https://doi.org/10.1038/1911017b0
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