Abstract
MORE than ten years ago Bonner1 made an unsuccessful attempt to use inactive variants and biochemical mutants of Penicillium chrysogenum for studying the mechanism of penicillin biosynthesis. Since that time the mechanism of the biosynthesis of the antibiotic has apparently not been investigated in this way.
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References
Bonner, D., Arch. Biochem., 3, 1 (1947).
Mindlin, S. Z., and Alikhanian, S. I., Doklady Akademyi Nauk SSSR, 111, 4, 884 (1956).
Selzer, G. B., Wright, W. W., Antibiot. and Chemother., 7, 6, 292 (1957).
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ALIKHANIAN, S., ORLOVA, N., MINDLIN, S. et al. Genetic Control of Oxytetracycline Biosynthesis. Nature 189, 939–940 (1961). https://doi.org/10.1038/189939b0
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DOI: https://doi.org/10.1038/189939b0
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