Abstract
ALTHOUGH the part played by intestinal alkaline phosphatase in digestion and absorption is still not clear, it has long been postulated that the high concentration in the duodenum and intestine is concerned with the absorption of glucose1. Following adrenal-ectomy, Verzar et al. 2,3 showed that intestinal alkaline phosphatase was reduced and glucose absorption decreased. Administration of adrenal cortical hormones caused regeneration of the phosphatase.
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References
Verzar, F., and MacDougal, Absorption, from the Intestine (Longmans, Green and Co., London, 1936).
Verzar, F., Sailer, E., and Richterich, R., Helv. Physiol. et Pharmacol. Acta, 10, 231 (1952).
Verzar, F., and Sailer, E., Helv. Physiol. et Pharmacol. Acta, 10, 247 (1952).
Sobotka, H., Physiological Chemistry of the Bile (Baltimore, 1937).
Barter, R., and Danielli, J. F., Proc. Roy. Soc., B, 144, 412 (1955).
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BROWN (née BOWYER), F. Role of Biliary Alkaline Phosphatase in the Guinea Pig. Nature 189, 755–756 (1961). https://doi.org/10.1038/189755a0
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DOI: https://doi.org/10.1038/189755a0
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