Abstract
INTRAVENOUS administration of guanethedine has been reported to cause a pressor response1,2, contraction of the nictitating membrane of the cat and pilo-erection2; the pressor response was not blocked by ganglionic blocking agents2. These phenomena lead to the possible conclusion that guanethedine causes a release of catecholamines or has some direct adrenergic effects.
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References
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WYLIE, D. Augmentation of the Pressor Response to Guanethedine by Inhibition of Catechol O-Methyltransferase. Nature 189, 490–491 (1961). https://doi.org/10.1038/189490a0
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DOI: https://doi.org/10.1038/189490a0
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Orientierende Übersicht
Ergebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie (1966)
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