Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Genetic Recombination in Bacteriophage ΦX 174

Abstract

RECENTLY, Tessman1,2 and Sinsheimer3 suggested that the deoxyribonucleic acid of ΦX 174 is one-stranded in contrast to the double-stranded deoxyribonucleic acid of other phages. From this point of view it seemed interesting to investigate genetic recombination in this phage. Tessman4 achieved recombination in bacteriophage S 13 by stimulation with ultra-violet irradiation of free virus particles. (S 13 is serologically related to ΦX 174 and similar in other properties.) The frequency of recombinants found after ultra-violet irradiation was of the order of 0.1 per cent. In other work5 without irradiation, no recombination could be detected.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Tessman, I., Virology, 7, 263 (1959).

    Article  CAS  Google Scholar 

  2. Tessman, I., Virology, 9, 375 (1959).

    Article  CAS  Google Scholar 

  3. Sinsheimer, R. L., J. Mol. Biol., 1, 45 (1959).

    Google Scholar 

  4. Tessman, E., and Tessman, I., Virology, 7, 465 (1959).

    Article  CAS  Google Scholar 

  5. Zahler, S. A., J. Bact., 75, 310 (1958).

    CAS  PubMed  Google Scholar 

  6. Streisinger, G., Cold Spring Harbor Symp., 21, 103 (1956).

    Article  CAS  Google Scholar 

  7. Bresch, C., and Trautner, T., Z. Vererbl., 87, 590 (1956).

    CAS  Google Scholar 

  8. Schuster, H., and Schramm, G., Z. Naturf., 13, b, 697 (1958). Mundry, K. W., and Gierer, A., Z. Vererbl., 89, 614 (1958).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

PFEIFER, D. Genetic Recombination in Bacteriophage ΦX 174. Nature 189, 422–423 (1961). https://doi.org/10.1038/189422a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/189422a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing