Abstract
OF the tissues of several animal species the myocardium has the highest concentration of glutamic oxaloacetic transaminase (GOT)1–3. Distribution of this enzyme in several zones of the cardiac muscle has received but scant attention in the literature. However, it has been shown that the dog's left ventricle has a higher GOT activity than the right one4, and a similar difference has been described for the concentration of adenosine tri-phosphatase and succinic dehydrbgenase5. On the other hand, Jennings, Kaltenbach and Smetters failed to note significant differences in the left ventricle of the dog between the GOT activity of the posterior papillary muscle, the left ventricle immediately beneath, and the anterior superior septum6. The present observations show that GOT activity of the myocardium is not uniform, and that there are significant differences in dogs among several zones of both ventricles.
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GIMENO, A., FERNÁNDEZ DE GIMENO, M., SAVINO, E. et al. Glutamic Oxaloacetic Transaminase Activity in Different Zones of the Ventricular Muscle of the Dog. Nature 189, 315–316 (1961). https://doi.org/10.1038/189315a0
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DOI: https://doi.org/10.1038/189315a0
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