Abstract
THE rate of conversion of administered inorganic radioiodine into protein-bound radioiodine of the plasma has been used frequently to evaluate thyroid activity in mammals. The test is recognized as having good discriminatory power in higher vertebrates1,2, but the relatively large sample of blood required for separation of serum by the usual methods has made the test impractical for small fish. A method is described here for determining protein-bound radioiodine as an in vivo test in fish of 30 gm. or more and as a terminal test in fish as small as 1 gm.
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References
Clark, D. E., Moe, R. H., and Adams, E. E., Surgery, 26, 331 (1949).
Lachiver, E., and Poivilliers de la Queriere, F., Z. vergleich. Physiol., 42, 6 (1959).
Riggs, D. S., Pharm. Rev., 4, 284 (1952).
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HICKMAN, C. The Conversion Ratio as a Discriminatory Test for Thyroid Activity in Fish. Nature 189, 1012–1013 (1961). https://doi.org/10.1038/1891012a0
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DOI: https://doi.org/10.1038/1891012a0
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