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Senile Dementia and Cerebral Oxygen Uptake measured on the Right and Left Sides

Abstract

IN a recently concluded work1 on cerebral oxygen uptake in the aged, an unexpected result was that uptake values based on blood drawn from the left internal jugular vein were more closely related to mental function than were values based on right jugular blood. Five normal aged men and nine male patients with, chronic brain syndrome were included in this part of the investigation. Bilateral cerebral oxygen uptake determinations were made with Lassen and Munck's modification2 of the inert gas method of Kety and Schmidt3. This modification employs krypton-85 as the inert gas, and bilateral simultaneous sampling of internal jugular blood is carried out. Psychological functioning was assessed by the Wechsler adult intelligence scale and Raven's matrices4. The physiological and psychometric data were not compared until after completion of the investigation.

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FEINBERG, I., LANE, M. & LASSEN, N. Senile Dementia and Cerebral Oxygen Uptake measured on the Right and Left Sides. Nature 188, 962–964 (1960). https://doi.org/10.1038/188962b0

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