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Schistosomiasis and Urinary β-Glucuronidase Activity

Abstract

Boy land, Wallace and Williams1 have shown that the activity of urinary β-glucuronidase is increased in patients suffering from bladder cancer and suggested that ‘spontaneous’ urinary bladder cancer could be caused by unmasking carcinogens which were inactive as β-glucuronides, but active when liberated by β-glucuronidase in the urine.

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References

  1. Boyland, E., Wallace, D. M., and Williams, D. C., Brit. J. Cancer, 9, 62 (1955).

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  2. Prates, M. D., and Gillman, J. S., S. Afr. J. Med. Sci., 24, 13 (1959).

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  3. Boyland, E., Gasson, J. E., and Williams, D. C., Brit. J. Cancer, 11, 120 (1957).

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  4. Lewis, F. J. W., and Plaice, Constance H. J., Nature, 184, 1249 (1959).

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FRIPP, P. Schistosomiasis and Urinary β-Glucuronidase Activity. Nature 188, 507–508 (1960). https://doi.org/10.1038/188507a0

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