Abstract
THE enzymatic deamination of deoxycytidylic acid to deoxyuridylic acid in sea urchin eggs and embryos has been demonstrated by Scarano1 and Scarano and Maggio2. Moreover, later results obtained by Scarano and Tallarico3 on the presence of deoxycytidylic acid-deaminase in livers of rat, chicken, rabbit in various stages of their embryonic development may indicate that this enzymatic activity, in developing or regenerating tissues, is proportional to their growth-rate. This latter view was confirmed in experiments by Maley and Maley4 on the determination of this enzymatic activity in embryonic tissues, in some spontaneous and experimental tumours and in regenerating livers.
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References
Scarano, E., Biochim. Biophys. Acta, 29, 459 (1958).
Scarano, E., and Maggio, R., Exp. Cell Res., 18, 333 (1959).
Scarano, E., and Tallarico, G., Boll. Soc. Ital. Biol. Sper., 35, 13 (1959).
Maley, G. F., and Maley, F., J. Biol. Chem., 234, 11 (1959).
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GUERRITORE, D., ROCCHI, V. & SETZU, A. 5-Deoxycytidylic Acid-deaminating Activity in Human Gastric Mucosa and Other Adult Mammalian Tissues. Nature 188, 146–147 (1960). https://doi.org/10.1038/188146b0
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DOI: https://doi.org/10.1038/188146b0
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