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Ubiquinone (50) and Ubichromenol in Aspergillus fumigatus, Fresenius

Abstract

FOLLOWING the recent discovery1–5 of a series of ubiquinones in various biological tissues, a useful system for studying their biosynthesis was sought. A strain of Aspergillus fumigatus, Fresenius (we wish to thank Prof. J. H. Birkinshaw for the gift of a specimen culture), studied by Anslow and Raistrick6, was observed to secrete 3-hydroxy, 4-methoxy, 2,5-toluquinone (fumigatin) into the medium. This compound is closely related to the ring nucleus of ubiquinone and it seemed possible that the above organism might also produce sufficient ubiquinone for the study of its biosynthesis.

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References

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PACKTER, N., GLOVER, J. Ubiquinone (50) and Ubichromenol in Aspergillus fumigatus, Fresenius. Nature 187, 413–414 (1960). https://doi.org/10.1038/187413b0

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