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Nature of the Hæm-Binding Groups in Native and Denatured Hæmoglobin and Myoglobin

Nature volume 187, pages 365–371 (1960)Cite this article

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References

  1. Redfield, A. C., Quart. Rev. Biol., 8, 31 (1933).

    Article  CAS  Google Scholar 

  2. Keilin, D., Acta Biochim. Polonica, 3, 439 (1956).

    CAS  Google Scholar 

  3. Itano, H. A., “Adv. Protein Chem.”, 12, 215 (1957).

    Article  CAS  Google Scholar 

  4. Ingram, V. M., Brit. Med. Bull., 15, 27 (1959).

    Article  CAS  Google Scholar 

  5. Lehmann, H., Brit. Med. Bull., 15, 40 (1959).

    Article  CAS  Google Scholar 

  6. Wyman, J., “Adv. Protein Chem.”, 4, 407 (1948).

    Article  CAS  Google Scholar 

  7. Coryell, C. D., and Pauling, L., J. Biol. Chem., 132, 769 (1940).

    CAS  Google Scholar 

  8. Lemberg, R., and Legge, J. W., “Hæmatin Compounds and Bile Pigments” (Intersci. Pub., 1949).

    Google Scholar 

  9. Roughton, F. J. W., “Harvey Lect.”, 39, 96 (1943–44).

    Google Scholar 

  10. O'Hagan, J. E., Nature, 183, 393 (1959).

    Article  ADS  CAS  Google Scholar 

  11. Haurowitz, F., see discussion p. 48 in Conference on Hemoglobin, Pub. 557, National Academy Sciences (Washington, D.C., 1958).

  12. Haurowitz, F., Hoppe-Seyl. Z., 232, 146 (1935).

    Article  CAS  Google Scholar 

  13. Tristram, G. R., “The Amino Acid Composition of Proteins”, in “The Proteins”, 1 A, 181, edit. Neurath, H., and Bailey, K. (Academic Press, New York, 1953).

    Google Scholar 

  14. Riggs, A., J. Gen. Physiol., 36, 1 (1952).

    Article  CAS  Google Scholar 

  15. Riggs, A., Nature, 183, 1037 (1959).

    Article  ADS  CAS  Google Scholar 

  16. Haurowitz, F., and Hardin, R. L., “Respiratory Proteins”, in “The Proteins”, 2 A, 279, edit. Neurath, H., and Bailey, K. (Academic Press, New York, 1954).

    Google Scholar 

  17. Hirsch, M., “Zur Kenntnis der Blutfarbstoffe”, doctoral dissertation, Heidelberg (1934).

    Google Scholar 

  18. Keilin, J., “Reactions of Porphyrins and Metalloporphyrins with Nitrogenous Substances and Their Bearing on the Structure of Hæmoglobin”, dissertation, Univ. Cambridge (1951).

    Google Scholar 

  19. Hill, R., Proc. Roy. Soc., B, 100, 419 (1926).

    Article  ADS  CAS  Google Scholar 

  20. Keilin, J., Biochem. J., 45, 448 (1949).

    Article  CAS  Google Scholar 

  21. Hill, R., Proc. Roy. Soc., B, 105, 112 (1929).

    Article  ADS  CAS  Google Scholar 

  22. Krebs, H. A., Biochem. Z., 204, 322 (1929).

    CAS  Google Scholar 

  23. Drabkin, D. L., J. Biol. Chem., 142, 855 (1942); 146, 605 (1942).

    CAS  Google Scholar 

  24. Anson, M. L., and Mirsky, A. E., J. Gen. Physiol., 12, 273 (1928–29).

    Article  CAS  Google Scholar 

  25. Holden, H. F., and Freeman, M., Aust. J. Exp. Biol. Med. Sci., 6, 79 (1929).

    Article  CAS  Google Scholar 

  26. Zeile, K., and Gnant, G., Hoppe-Seyl. Z., 263, 147 (1940).

    Article  CAS  Google Scholar 

  27. Keilin, J., Nature, 165, 151 (1950).

    Article  ADS  CAS  Google Scholar 

  28. Drabkin, D. L., J. Biol. Chem., 158, 721 (1945).

    CAS  Google Scholar 

  29. Rosenberg, L. L., and Clark, W. M., J. Biol. Chem., 205, 617 (1953).

    CAS  PubMed  Google Scholar 

  30. Barron, E. S. G., J. Biol. Chem., 121, 285 (1937).

    CAS  Google Scholar 

  31. Langenbeck, W., Ber. dtsch. chem. Ges., 65, 842 (1932).

    Article  Google Scholar 

  32. Cowgill, R. W., and Clark, W. M., J. Biol. Chem., 198, 33 (1952).

    CAS  Google Scholar 

  33. Keilin, D., Nature, 171, 922 (1953).

    Article  ADS  CAS  Google Scholar 

  34. Kendrew, J. C., and Parrish, R. G., Nature, 175, 206 (1955).

    Article  ADS  CAS  Google Scholar 

  35. George, P., and Lyster, R. L. J., in Conference on Hemoglobin, 33, Pub. 557, National Academy Sciences (Washington, D.C., 1958).

  36. Hill, R., and Holden, H. F., Biochem. J., 20, 1326 (1926).

    Article  CAS  Google Scholar 

  37. Granick, S., “Harvey Lect.”, 44, 220 (1949).

    Google Scholar 

  38. Anson, M. L., “Adv. Protein Chem.”, 2, 361 (1945).

    Article  CAS  Google Scholar 

  39. Zeynek, R., Now. Lek., 38, 406 (1926).

    Google Scholar 

  40. Haurowitz, F., J. Biol. Chem., 193, 443 (1951).

    CAS  PubMed  Google Scholar 

  41. Keilin, D., and Hartree, E. F., Nature, 170, 161 (1952).

    Article  ADS  CAS  Google Scholar 

  42. Kobert, R., Jahrber. Fortschr. Tierchem., 21, 443 (1891).

    Google Scholar 

  43. Stitt, F., and Coryell, C. D., J. Amer. Chem. Soc., 61, 1263 (1939).

    Article  CAS  Google Scholar 

  44. Kiese, M., and Kaeske, H., Biochem. Z., 312, 121 (1942).

    CAS  Google Scholar 

  45. Keilin, J., Biochem. J., 59, 571 (1955).

    Article  CAS  Google Scholar 

  46. Keilin, D., and Hartree, E. F., Biochem. J., 61, 153 (1955).

    Article  CAS  Google Scholar 

  47. Kendrew, J. C., Dickerson, R. E., Strandberg, B. E., Hart, R. G., Davies, D. R., Phillips, D. C., and Shore, V. C., Nature, 185, 422 (1960).

    Article  ADS  CAS  Google Scholar 

  48. Perutz, M. F., Rossmann, M. G., Cullis, A. F., Muirhead, H., Will, G., and North, A. C. T., Nature, 185, 416 (1960).

    Article  ADS  CAS  Google Scholar 

  49. Kendrew, J. C., Bodo, G., Dintzis, H. M., Parrish, R. G., Wyckoff, H., and Phillips, D. C., Nature, 181, 662 (1958).

    Article  ADS  CAS  Google Scholar 

  50. Rossi-Fanelli, A., Antonini, E., and Povoledo, D., in “Symposium on Protein Structure”, 144, edit. Neuberger, A. (Methuen, London, 1958).

    Google Scholar 

  51. Roche, J., Bull. Soc. Chim. Biol., 16, 793 (1934).

    CAS  Google Scholar 

  52. Markham, R., and Smith, J. D., “Nucleoproteins and Viruses”, in “The Proteins”, 2 A, 1, edit. Neurath, H., and Bailey, K. (Academic Press, New York, 1954).

    Google Scholar 

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  1. School of Veterinary Medicine, University of Cambridge,

    JOAN KEILIN

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KEILIN, J. Nature of the Hæm-Binding Groups in Native and Denatured Hæmoglobin and Myoglobin. Nature 187, 365–371 (1960). https://doi.org/10.1038/187365a0

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