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Fibrinolytic Activity of Cirrhotic Liver

Abstract

SEVERAL investigators have observed increased fibrinolytic activity in the circulating blood in cases of liver cirrhosis in man1–4. The cause of this activity is unknown, though a toxic effect similar to that produced in dogs by chloroform or peptone has been suggested. Such a mechanism could possibly be involved in an acute process, but could barely explain the prolonged periods of increased fibrinolytic activity observed in cases of liver cirrhosis.

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ASTRUP, T., RASMUSSEN, J., AMERY, A. et al. Fibrinolytic Activity of Cirrhotic Liver. Nature 185, 619–620 (1960). https://doi.org/10.1038/185619a0

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