Abstract
RECENTLY, Kornberg et al. 1 have demonstrated that deoxyribonucleic acid formed in vitro by enzymatic synthesis has chemical and physical properties similar to the acid used as primer. Since exposure to radiation is known to cause chemical changes in deoxyribonucleic acid2–4, it was thought that such changes might be reflected in the newly synthesized acid. In an attempt to study this, we have determined the ability of irradiated and non-irradiated deoxyribonucleic acid to incorporate tritium-labelled thymidine or tritium-labelled deoxycytidylic acid in the presence of the deoxyribonucleic acid-synthesizing enzyme system from regenerating rat liver.
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OKADA, S. Incorporation of Tritium-labelled Thymidine and Tritium-labelled Deoxycytidylic Acid into Deoxyribonucleic Acid after Irradiation of the Deoxyribonucleic Acid Primer with γ-Rays. Nature 185, 193–194 (1960). https://doi.org/10.1038/185193a0
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DOI: https://doi.org/10.1038/185193a0
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