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Enzymes and Radioactivity in Erythrocytes of Different Ages

Abstract

FRACTIONATION of erythrocytes of different ages by differential hæmolysis is a useful approach to the study of enzymatic aspects of the maturation of the erythrocyte in the peripheral blood. Young red cells are thought to be resistant to osmotic hæmolysis and older cells to be very fragile1. Recently Simon and Topper2 have shown by serial osmotic hæmolysis that young erythrocytes have both fragile and resistant components. In the present paper the activities of glutamic oxaloacetic transaminase and lactic dehydrogenase have been related to red blood cells of various ages.

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References

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LEVY, L., WALTER, H. & SASS, M. Enzymes and Radioactivity in Erythrocytes of Different Ages. Nature 184, 643–644 (1959). https://doi.org/10.1038/184643a0

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