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Inhibition of Rous I Sarcoma Metastases by a Copper-Catalyst Blocking Agent

Nature volume 184, pages 1963–1964 (1959)Cite this article

Abstract

A CONNEXION has previously been demonstrated between the activation of copper-enzyme catalysis and the production of tanned lipoprotein surface membranes1. These same membranes, under various experimental conditions, were found to be nonadhesive2, and since tumour cell surfaces display this property3, it suggested the possibility that cellular adhesion may depend on the integrity of a proportion of the protein moiety of the lipoprotein complex of the surface membrane.

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References

  1. Jones, B. M., Proc. Roy. Soc., B, 149, 263 (1958).

    Article  ADS  CAS  Google Scholar 

  2. Jones, B. M., Symposium (1959), The Cell Surface, Proc. Roy. Phys. Soc. Edin. (to be published).

  3. Ambrose, E. J., Nature, 182, 1419 (1958).

    Article  ADS  Google Scholar 

  4. Dennell, R., and Malek, S. R. A., Proc. Roy. Soc., B, 144, 545 (1956).

    Article  ADS  CAS  Google Scholar 

  5. Louis, C. J., Brit. J. Cancer, 12, 537 (1958).

    Article  CAS  Google Scholar 

  6. Fitzpatrick, T. B., Becker, S. W., Lerner, A. B., and Montgomery, H., Science, 112, 223 (1950).

    Article  ADS  CAS  Google Scholar 

  7. Dawson, C. R., and Tarpley, W. B., ‘The Enzymes’, 2, Pt. 1 (New York, Acad. Press, 1951).

    Google Scholar 

  8. Wynne, E. S., ‘Pigment Cell Biology’, 432, edit. Gordon, M. (New York, Acad. Press, 1959).

    Google Scholar 

  9. Grant, W. C., and Krantz, J. C., Cancer Res., 2, 833 (1942).

    CAS  Google Scholar 

  10. Slater, E. C., ‘Adv. Enzymol.’, 20, 147 (1958).

    CAS  Google Scholar 

  11. More, T., Nature, 184, 607 (1959).

    Article  ADS  Google Scholar 

  12. Williams-Ashman, H. G., Cassman, M., and Klavins, M., Nature, 184, 427 (1959).

    Article  ADS  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Zoology, University of Edinburgh,

    B. M. JONES

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  1. B. M. JONES
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JONES, B. Inhibition of Rous I Sarcoma Metastases by a Copper-Catalyst Blocking Agent. Nature 184, 1963–1964 (1959). https://doi.org/10.1038/1841963b0

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