Abstract
THE affinity of arsenicals for sulphydryl groups was first suggested by Ehrlich as being responsible for the toxic action of these poisons, and the work by Voegtlin1 and his associates later demonstrated that the trypanocidal action of arsenicals was reversed as well as prevented by the administration of reduced glutathione, cysteine and related sulphydryl compounds.
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References
Voegtlin, C., Dyer, H. A., and Leonard, C. S., J. Pharm. and Exp. Therap., 25, 297 (1925). Rosenthal, S. M., and Voegtlin, C., ibid, 39, 347 (1930).
Fink, D. E., J. Econ. Ent., 20, 794 (1927).
Forgash, A. J., ibid., 44, 870 (1951); 49, 39 (1956).
Harington, J. S. (unpublished).
Park, G. S., and Speakman, J. V., Bull. de l'Inst. text. de France, 30, 255 (1952).
Woodward, G. E., J. Biol. Chem., 109, 1 (1935).
Snell, F. D., and Snell, C. T., ‘Colorimetric methods of analysis’ Vol. 3, 3rd edit., 492 (New York, 1953).
Thompson, M. E., and Johnston, A. M., Nature, 181, 647 (1958).
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HARINGTON, J. Contents of Cystine-Cysteine, Glutathione and Total Free Sulphydryl in Arsenic-resistant and sensitive Strains of the Blue Tick, Boophilus decoloratus. Nature 184, 1739–1740 (1959). https://doi.org/10.1038/1841739b0
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DOI: https://doi.org/10.1038/1841739b0
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