Abstract
Prehn and Main1, in a review of the subject, state that the demonstration of circulating cytotoxins is much simpler when heterologous tissue transplants are used as antigens than when homologous tissues are used. Schrek and Preston2, using the Bagg rat lymphosarcoma in Sprague–Dawley rats, report the successful demonstration of serum cytotoxins in the rats (25 per cent of the total) in which the tumour had regressed.
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References
Prehn, R. T., and Main, J. M., J. Nat. Cancer Inst., 14, 537 (1953).
Schrek, Robert, and Preston, Frederick W., Surgical Forum of the American College of Surgeons (1954).
Coriell, Lewis L., Tall, Milton G., and Gaskill, Helen, Science, 128, 198 (1958).
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CRANSTON, H., EGGERT, F. Homologous Species Neoplastic Antibodies. Nature 183, 1471–1472 (1959). https://doi.org/10.1038/1831471b0
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DOI: https://doi.org/10.1038/1831471b0
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