Abstract
RECENTLY, Quastel and Bickis1 published a very interesting and stimulating article concerning the energy relationships in several intact cell types, including the Ehrlich ascites carcinoma cell. They determined the ratio of lactate produced to the difference between oxygen consumed in the cell system with and without added glucose (average value 5.8). The assumption was made that the amount of adenosine triphosphate produced in the two systems was the same. They reasoned that if the total production of energy remained constant in the two cell systems, the ratio phosphorus/oxygen would be about 3.
Similar content being viewed by others
Article PDF
References
Quastel, J. H., and Bickis, I. J., Nature, 183, 281 (1959).
Ibsen, K. H., Coe, E. L., and McKee, R. W., Biochim. Biophys. Acta, 30, 384 (1958).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
IBSEN, K., COE, E. & McKEE, R. Energy Compensation in the Crabtree Effect with Ehrlich Ascites Carcinoma Cells. Nature 183, 1471 (1959). https://doi.org/10.1038/1831471a0
Issue Date:
DOI: https://doi.org/10.1038/1831471a0
This article is cited by
-
Relationship between of blood flow, glucose metabolism, protein synthesis, glucose and ATP content in experimentally-induced glioma (RG12.2) of rat brain
Journal of Neuro-Oncology (1990)
-
�ber die Beeinflussung von Reaktionen des Citronens�ure-Cyclus durch 2-Desoxy-D-Glucose
Zeitschrift f�r Krebsforschung (1960)
-
Über die Abhängigkeit des Sauerstoffverbrauches von Ehrlich-Ascites-Carcinomzellen von der Oxydation der Glucose über den Hexose-Monophosphat-Shunt
Zeitschrift für Krebsforschung (1960)
-
Efficiency of the Mitochondrial Oxidative Phosphorylations in Intact Ascites Tumour Cells
Nature (1959)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.