Abstract
THE successful culture of embryonic chick femora and tibiæ on a chemically defined medium has recently been described1. The medium used was No. 8582, which was originally designed for the culture of Earle's L-strain cells. We have now been able to cultivate embryonic rat tibiæ on a closely related, chemically defined medium (J. D. Biggers and J. A. Lucy, unpublished work), thus paving the way for future studies on the specific nutritional requirements and metabolism of growing mammalian cartilage.
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References
Biggers, J. D., Webb, M., Parker, R. C., and Healy, G. M., Nature, 180, 825 (1957).
Healy, G. M., Fisher, D. C., and Parker, R. C., Proc. Soc. N.Y. Exp. Biol., 89, 71 (1955).
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Bhaskar, S. N., Weinmann, J. P., and Schour, I., Anat. Rec., 119, 231 (1954).
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HEYNER, S., BIGGERS, J. Cultivation of Isolated Embryonic Rat Tibiæ on a Chemically Defined Medium. Nature 182, 810–811 (1958). https://doi.org/10.1038/182810a0
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DOI: https://doi.org/10.1038/182810a0
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