Abstract
IN a recent publication and its addendum by Dickens and Williamson and by Bellamy and Williams1, it was reported that the infra-red spectra of lithium pyruvate and hydroxypyruvate in the solid state show no ketonic carbonyl peak, and it was suggested that these compounds exist as the hydrate, RCH2C(OH)2COO−Li+, in the solid and in aqueous solution and that this hydrate may be the substrate for the enzymatic reduction of pyruvate to lactate at neutral pH.
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References
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JENCKS, W., CARRIUOLO, J. Structure of Pyruvate in Aqueous Solution. Nature 182, 598–599 (1958). https://doi.org/10.1038/182598b0
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DOI: https://doi.org/10.1038/182598b0
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