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Ringed Appearance of Lipid Spheres under the Phase-Contrast Microscope

Abstract

RECENTLY, Chou and Bradbury1 have pointed out some optical artefacts produced in the appearance of fat droplets under the phase-contrast microscope. They say that homogeneous fat droplets may have a “crescentic” appearance if examined in a non-axial light source or an eccentric condenser. They also point out that in a fully centred system the appearance of such a fat globule is a “perfectly symmetrical sphere with a dark rim or apparent ‘cortex’ surrounding the bright region within”.

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References

  1. Chou, J. T. Y., and Bradbury, S., Nature, 179, 1243 (1957).

    Article  ADS  Google Scholar 

  2. Nath, V., Res. Bull. Panjab Univ., 95–99, 1 (1957).

    Google Scholar 

  3. Gupta, B. L., Nature, 181, 555 (1958).

    Article  ADS  CAS  Google Scholar 

  4. Roque, A. L., J. Roy. Micr. Soc., 74, 188 (1954).

    Article  CAS  Google Scholar 

  5. Nath, V., and Gupta, B. L., Quart. J. Micro. Sci., 97, 369 (1956).

    Google Scholar 

  6. Rishi, R., Quart. J. Micro. Sci., 97, 171 (1956).

    Google Scholar 

  7. Rishi, R., Quart. J. Micro. Sci., 98, 235 (1957).

    Google Scholar 

  8. Baker, J. R., Nature, 180, 947 (1957).

    Article  ADS  CAS  Google Scholar 

  9. Baker, J. R., Quart. J. Micro. Sci., 85, 1 (1944).

    Google Scholar 

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GUPTA, B. Ringed Appearance of Lipid Spheres under the Phase-Contrast Microscope. Nature 182, 537–538 (1958). https://doi.org/10.1038/182537a0

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