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Effects of Flavin Monosulphate and Flavin Adenine Dinucleotide on the Electroencephalogram

Abstract

FLAVIN MONOSULPHATE (riboflavin-5′-monosulphate) has been found to inhibit D-amino-acid oxidase in competition with flavin adenine dinucleotide1. On the other hand, it was supposed that flavin adenine dinucleotide might have some important role in the brain since it reversed the inhibitory action of chlorpromazine on the oxidation of amino-acids by a homogenate of the diencephalon part of the brain2. Taking these results into consideration, the effects of flavin monosulphate and flavin adenine dinucleotide on the function of the brain were examined by electroencephalography.

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References

  1. Egami, F., and Yagi, K., J. Biochem. (Japan), 43, 153 (1956).

    Article  CAS  Google Scholar 

  2. Yagi, K., Nagatsu, T., and Ozawa, T., Nature, 177, 891 (1956).

    Article  ADS  CAS  Google Scholar 

  3. Takahashi, N., Yagi, K., and Egami, F., J. Chem. Soc. Japan, Pure Chem. Sect., 78, 1287 (1957).

    CAS  Google Scholar 

  4. Yagi, K., Matsuoka, Y., Kuyama, S., and Tada, M., J. Biochem. (Japan), 43, 93 (1956).

    Article  CAS  Google Scholar 

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MURAMATSU, T., ANDO, M., NAGATSU, T. et al. Effects of Flavin Monosulphate and Flavin Adenine Dinucleotide on the Electroencephalogram. Nature 182, 457–458 (1958). https://doi.org/10.1038/182457a0

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