Abstract
We have recently suggested1 that the secretion of the adrenal cortex exerts a functional control over the levels in tissue of both histamine and 5-hydroxytryptamine. This evidence was obtained by injecting synthetic corticosteroid substances into normal rats as well as into rats in which tissue histamine had been previously depleted. Further experiments have now been carried out on animals the adrenal glands of which have been removed before drug treatment.
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References
Hicks and West, Nature, 181, 1342 (1958).
Schayer, Smiley and Davis, Proc. Soc. Exp. Med. Biol., 87, 590 (1954).
Rose and Browne, Amer. J. Physiol., 131, 589 (1941).
Parratt and West, J. Physiol., 137, 169 (1957).
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HICKS, R., WEST, G. Adrenalectomy and Tissue Amines. Nature 182, 401–402 (1958). https://doi.org/10.1038/182401b0
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DOI: https://doi.org/10.1038/182401b0
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