Abstract
IT has been well established that adrenocortical steroids have a pronounced effect on carbohydrate metabolism, in particular on the level of liver glycogen. Various methods for the assay of adrenocorticoids have been reported1,2, based upon the ability of these substances to cause a deposition of glycogen in the livers of adrenalectomized rats and mice. However, all these methods appear to be sufficiently complex and tedious to exclude their use when rapid screening procedures are desired. Van der Vies3 has described two colorimetric methods for the determination of glycogen in body tissues.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Eggleston, N. M., Johnston, B. J., and Dobriner, K., Endocrinol., 38, 197 (1946). Olson, R. E., Jacobs, F. A., Richert, D., Thayer, S. A., Kopp, L. J., and Wade, N. J., ibid., 35, 430 (1944). Pabst, M. L., Sheppard, R., and Kuizenga, M. H., ibid., 41, 55 (1947). Reinecke, R. M., and Kendall, E. C., ibid., 31, 573 (1942).
Venning, E. H., Kazmin, V., and Bell, J. C., Endocrinol., 38, 79 (1946).
Van der Vies, J., Biochem. J., 57, 410 (1954).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BLOCK, B., D'ARCY, P. A Simple and Rapid Method for the Biological Assay of Glucocorticoids. Nature 182, 181–182 (1958). https://doi.org/10.1038/182181a0
Issue Date:
DOI: https://doi.org/10.1038/182181a0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
