Abstract
PLASMA kinin1 (originally named “pain-producing substance”2) is a pain-producing and smooth muscle-contracting polypeptide which can be released from human blood plasma in a number of ways, including contact with glass and some other surfaces. The mechanism of kinin release by contact has been resolved into two stages : in the first, ‘contact factor’ is formed from its precursor (‘component A’) ; in the second ‘contact factor’ reacts with another constituent (‘component B’)1,3.
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References
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MARGOLIS, J. Hageman Factor in Plasma Foreign Surface Reactions. Nature 182, 1102–1103 (1958). https://doi.org/10.1038/1821102a0
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DOI: https://doi.org/10.1038/1821102a0
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