Abstract
HAVING been informed that we had succeeded in isolating 16β-hydroxyœstrone from the urine of pregnant women, Dr. T. F. Gallagher of the Sloan-Kettering Institute, New York, most courteously suggested to us that we should publish a preliminary account of our work simultaneously with his own announcement of the detection of the same compound by reverse isotope dilution in the urine of a human subject after the administration of œstradiol-17β-16-14C (succeeding communication). The completion of our own work would have been delayed by many months if Dr. Gallagher had not provided us, before publication, with details of his method1 for synthesizing 16β-hydroxyœstrone from œstrone via the enol diacetate of the latter. It is a pleasure to acknowledge his generous co-operation.
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LAYNE, D., MARRIAN, G. Isolation of 16β-Hydroxyœstrone from the Urine of Pregnant Women. Nature 182, 50 (1958). https://doi.org/10.1038/182050a0
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DOI: https://doi.org/10.1038/182050a0
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