Abstract
VERDOHÆM is an interesting intermediate through which the conversion of hæmin into biliverdin was first achieved1. In a recent paper2, Rackow discusses its structure. He refers only to my first paper1, but not to later papers3–5 in which a modified formula with a ring containing an oxygen atom instead of one carbon atom of the porphyrin ring was suggested on the basis of new evidence. The structure suggested by Rackow is that of a pyridinium salt of an α-hydroxyporphyrin–iron complex carrying on its iron atom one molecule of pyridine and one molecule of oxygen bound as in oxyhæmoglobin.
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References
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LEMBERG, R. Constitution of Verdohæm. Nature 181, 1131–1132 (1958). https://doi.org/10.1038/1811131b0
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DOI: https://doi.org/10.1038/1811131b0
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