Abstract
IN the development of the nervous system of the vertebrate embryo, the spinal nerves grow outwards to the developing limb-buds. Once within the limb rudiment, nerve fibres apparently convey some trophic stimulus to their cell bodies, at the levels of the brachial and lumbar plexuses. This influence can be demonstrated by removal of a limb on one side of an embryo, when both the sensory neurones of the dorsal root ganglia1 and the motor neurones of the ventral horns within the cord2 have been shown to be fewer in number on the operated side.
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HUGHES, A., TSCHUMI, P. Transmission of Trophic Stimuli along Developing Nerve Fibres. Nature 180, 999–1000 (1957). https://doi.org/10.1038/180999a0
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DOI: https://doi.org/10.1038/180999a0
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