Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Effect of Diisopropylphosphorofluoridate on the Acetylcholine Content of Flies

Abstract

PREVIOUS studies1,2 of the action of diisopropylphosphorofluoridate (DFP) on insects have been primarily concerned with the inhibition of cholin esterase, but nothing has been reported about its effect on the acetylcholine (ACh) content. We have therefore examined the effect of diisopropylphosphorofluoridate on acetylcholine-levels in the blowfly (Calliphora erythrocephala) and the housefly (Musca domestica).

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Chadwick, L. E., and Hill, D. L., J. Neurophysiol., 10, 235 (1947).

    Article  CAS  Google Scholar 

  2. Metcalf, R. L., and March, R. B., J. Econ. Ent., 43, 670 (1950).

    Article  CAS  Google Scholar 

  3. Lewis, S. E., and Smallman, B. N., J. Physiol. (in the press).

  4. Winteringham, F. P. W., and Harrison, A., Nature [178, 81 (1956)].

    Article  ADS  CAS  Google Scholar 

  5. Winteringham, F. P. W., and Harrison, A. (personal communication).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

LEWIS, S., FOWLER, K. Effect of Diisopropylphosphorofluoridate on the Acetylcholine Content of Flies. Nature 178, 919–920 (1956). https://doi.org/10.1038/178919a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/178919a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing