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The Small Saphenous Vein as a Route for Intravenous Injection in the White Rat

Abstract

A NUMBER of years ago, in searching for an accessible vessel from which blood could readily be obtained several times a week, we found that the small saphenous vein could easily be visualized and entered through the skin on the dorsum of the rat's foot. This vessel has since proved far more satisfactory than the commonly used tail vein for either bleeding or injection1,2. The technique of injection by this route has been briefly, but obscurely, described2, and it thus remains not generally known.

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References

  1. Sawyer, C. H., and Everett, J. W., Endocrin., 39, 307 (1946).

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  2. Sawyer, C. H., Everett, J. W., and Markee, J. E., Endocrin., 44, 218 (1949).

    Article  CAS  Google Scholar 

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EVERETT, J., SAWYER, C. The Small Saphenous Vein as a Route for Intravenous Injection in the White Rat. Nature 178, 268–269 (1956). https://doi.org/10.1038/178268b0

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