Abstract
Bell, Archer and Tomlin1, using the thromboplastin generation test, recently found the prolonged clotting time of horse blood to be due to a deficiency of anti-hæmophilic factor. However, Soulier and Larrieu2 have used horse plasma as a source of this factor. The thrombin generation test3,4 is useful in differentiating between classical hæmophilia and Christmas disease5. Applied to citrated horse plasma (containing 130,000 platelets per c.mm.) the following results were obtained (Fig. 1).
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Bell, W. N., Archer, R. K., and Tomlin, S. C., Nature, 175, 596 (1955).
Soulier, J. P., and Larrieu, M. J., J. Lab. Clin. Med., 41, 849 (1953).
Macfarlane, R. G., and Biggs, R., J. Clin. Path., 6, 9 (1953).
Pitney, W. R., and Dacie, J. V., J. Clin. Path., 6, 9 (1953).
Sjølin, K.-E., Scand. J. Lab. Clin. Invest. (in the press).
Aggeler, P. M., Spaet, T. H., and Byron, E. E., Science, 119, 806 (1954).
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SJØLIN, KE. Lack of Christmas Factor in Horse Plasma. Nature 178, 153 (1956). https://doi.org/10.1038/178153a0
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DOI: https://doi.org/10.1038/178153a0
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