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Acquired Resistance to Chloroquine Diphosphate in P. gallinaceum in Chicks

Nature volume 178, pages 1291–1292 (1956)Cite this article

Abstract

PAST experiments have shown that acquired resistance in Plasmodia to antimalarials can be developed easily and in a short time in certain groups of compounds. Per contra, such resistance to some other groups of anti-malarials can be built up either with difficulty or not at all. Proguanil and pyrimethamine belong to the former group, and it is noted that a Plasmodium made resistant to one becomes resistant also to the other1–3.

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Authors and Affiliations

  1. Malaria Institute of India, Delhi

    A. P. RAY & G. K. SHARMA

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  1. A. P. RAY
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  2. G. K. SHARMA
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RAY, A., SHARMA, G. Acquired Resistance to Chloroquine Diphosphate in P. gallinaceum in Chicks. Nature 178, 1291–1292 (1956). https://doi.org/10.1038/1781291a0

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