Abstract
Beeson and Goebel1 followed up earlier observations that human erythrocytes are agglutinated by Type XIV anti-pneumococcus horse serum2 with the demonstration that blood group A substance obtained from commercial pepsin precipitated with the Type XIV antiserum. Subsequent studies have shown that blood group substances isolated from hog gastric mucin, human saliva and human stomachs by peptic digestion cross-react with anti-Type XIV serum3. Human blood group A, B or H substances isolated from ovarian cyst fluids by the phenol extraction method4 do not precipitate to any appreciable extent in this system; but a strong cross-reactivity is developed after mild hydrolysis with acid5 or by treatment with specific enzymes6.
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References
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WATKINS, W., MORGAN, W. Role of a D-glucosamine as Inhibitor of the Precipitation of Blood Group Substances by Anti-Type XIV Pneumococcus Serum. Nature 178, 1289–1290 (1956). https://doi.org/10.1038/1781289a0
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DOI: https://doi.org/10.1038/1781289a0
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