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Sialoadenectomy and the Metabolism of Calcium-45 in Bone and Soft Tissues of the Mouse

Nature volume 178, pages 1229–1230 (1956)Cite this article

Abstract

IT has been reported that there are substances extractable from salivary glands which, when administered to animals, lead to a reduction of the plasma calcium1. Further observations2 indicated the extracted proteins to be capable of promoting the calcification of hard tissues. Sialoadenectomy has been reported to reduce markedly the total ash, calcium, magnesium and phosphorus of the bones of the rat3. Our observation4 that sialoadenectomized rats and mice exhibited reduced rates of growth, plus the study of Mari5, who observed an increased growth-rate in chick embryo femurs, suggested that we study the metabolism of calcium in intact and sialoadenectomized animals.

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References

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Authors and Affiliations

  1. Division of Biological Chemistry, Hahnemann Medical College, Philadelphia, Pennsylvania

    ARTHUR W. WASE & YU SHENG LOUISE FENG

Authors
  1. ARTHUR W. WASE
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  2. YU SHENG LOUISE FENG
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WASE, A., FENG, Y. Sialoadenectomy and the Metabolism of Calcium-45 in Bone and Soft Tissues of the Mouse. Nature 178, 1229–1230 (1956). https://doi.org/10.1038/1781229a0

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