Abstract
THE disappearance of neurones from the primate lateral geniculate body after de-afferentation has been clearly demonstrated1, and less dramatic transsynaptic degenerative changes have been described elsewhere in the central nervous system, for example, in the cortex of the piriform lobe after degeneration of the olfactory tract2. Hitherto, however, attention has been focused on the perikaryon, and the role of afferent input in preserving the normal dendritic organization of neurones has apparently never been studied.
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References
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Cajal, Santiago Ramon y, “Studies on the Cerebral Cortex” (Lloyd-Luke, Ltd., London, 1955).
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JONES, W., THOMAS, D. Trans-Synaptic Atrophy in the Cerebral Cortex. Nature 178, 47–48 (1956). https://doi.org/10.1038/178047b0
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DOI: https://doi.org/10.1038/178047b0
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