Abstract
IN 1954, Shaw et al. 1 showed that ββ-methylethyl glutarimide was capable of reducing the narcotic effect of barbiturates in animals and man, and suggested that in therapeutic dosage it exerts a direct antagonism to barbiturates.
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References
Shaw, F. H., Simon, S. E., Cass, N., Shulman, A., Anstee, J. R., and Nelson, E. R., Nature, 174, 402 (1954).
Jalling, O., Lindberg, O., and Ernster, L., Acta Chem. Scandinav., 9, 198 (1955).
Schneider, W. C., and Hogeboom, G. H., J. Biol. Chem., 183, 123 (1950).
Slater, E. C., and Cleland, K. W., Nature, 170, 118 (1952).
Berger, L., Slein, M., Colowick, S. P., and Cori, C. F., J. Gen. Physiol., 29, 379 (1946).
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JALLING, O. Effect of ββ-Methylethyl Glutarimide and Amytal on Rat-liver Mitochondrial Respiration. Nature 177, 330–331 (1956). https://doi.org/10.1038/177330b0
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DOI: https://doi.org/10.1038/177330b0
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