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Colicine K

Abstract

COLICINES are substances of unknown nature which are elaborated by certain strains of Entero-bacteriaceae and which have the ability to kill other strains within this group. At the time of their discovery some thirty years ago1, it was apparent that colicines bore a similarity to the bacteriophages, yet differed in that they could not be transmitted by serial passage. In recent years considerable attention has been paid these agents2, largely because of this relationship and because of a renewed interest in the bacteriophages themselves. The brilliant investigations of Fredericq have revealed that there are many different colicines; some seventeen specific types have thus far been described3. Furthermore, these agents are now known to be elaborated by microorganisms other than those of the enteric group. Because of this, the name ‘bacteriocines’ has been suggested to designate them4.

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References

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GOEBEL, W., BARRY, G., JESAITIS, M. et al. Colicine K . Nature 176, 700–701 (1955). https://doi.org/10.1038/176700a0

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