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Rat Liver Xanthine Oxidase in Carbon Tetrachloride Poisoning

Abstract

DURING the course of experiments dealing with the effect of some hepatotoxic drugs on rat liver xanthine oxidase, it was found that this enzyme is activated when carbon tetrachloride is administered in a single necrogenic dosage. The present communication presents results obtained in normal young rats injected subcutaneously with 0.1 ml./100 gm. body-weight.

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References

  1. Axelrod, A. E., and Elvehjem, C. A., J. Biol. Chem., 140, 725 (1941).

    CAS  Google Scholar 

  2. Dhungat, S. B., and Sreenivasan, A., J. Biol. Chem., 208, 845 (1954).

    CAS  PubMed  Google Scholar 

  3. Dixon, M., and Elliott, K. A. C., Biochem. J., 28, 812 (1929).

    Article  Google Scholar 

  4. Villela, G. G., Rev. Bras. Biol., [14, 455 (1954)].

    CAS  Google Scholar 

  5. Litwak, J. W., Bothwell, J. W., Williams, jun., J. N., and Elvehjem, C. A., J. Biol. Chem., 200, 303 (1953).

    Google Scholar 

  6. Forbes, J. C., and Neale, R. C., Proc. Soc. Exp. Biol. Med., 34, 319 (1936).

    Article  Google Scholar 

  7. Popper, H., Koch-Weser, D., and Szanto, P. B., Proc. Soc. Exp. Biol. Med., 71, 688 (1949).

    Article  CAS  Google Scholar 

Download references

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VILLELA, G., MITIDIERI, E. Rat Liver Xanthine Oxidase in Carbon Tetrachloride Poisoning. Nature 175, 208–209 (1955). https://doi.org/10.1038/175208a0

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