Abstract
PREVIOUS publications1,2 have reported on the incorporation of adenine-14C into ribonucleic acid and deoxyribonucleic acid by human bone marrow cells in vitro. Using a high-resolution autoradiography technique3, the grain counts over the individual cells before and after hydrolysis with Nhydrochloric acid at 60° C. for 6½ min. indicated a slightly larger amount of adenine-14C incorporated into ribonucleic than into deoxyribonucleic acid, in 24-hr, cultures (see Fig. 1).
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Lajtha, L. G., Nature, 173, 587 (1954).
Lajtha, L. G., Oliver, R., and Ellis, F., Brit. J. Cancer (in the press).
Lajtha, L. G., J. Phot. Sci. (in the press).
Smellie, R. M. S., McIndoe, W. M., and Davidson, J. N., Biochim. Biophys. Acta, 11, 559 (1953).
Payne, A. H., Kelly, L. S., Beach, G., and Jones, H. B., Cancer Research, 12, 426 (1952).
Totter, J. R., Abstr. 1st Meeting Rad. Res. Soc., Iowa City, Radiation Research, 1, 232 (1954).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
LAJTHA, L. Utilization of Formate-14C for Synthesis of Deoxyribonucleic Acid by Human Bone Marrow Cells in vitro. Nature 174, 1013–1014 (1954). https://doi.org/10.1038/1741013a0
Issue Date:
DOI: https://doi.org/10.1038/1741013a0
This article is cited by
-
Comparative rate of utilization of orotic acid and uridine by human and rat bone marrow cells during short-term cultivation
Bulletin of Experimental Biology and Medicine (1972)
-
Dependence of Bone Marrow Cells on the Liver for Purine Supply
Nature (1958)
-
Lack of Differential Radiation Effect on the Incorporation of Labelled Precursors into Deoxyribonucleic Acid
Nature (1957)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
